The Repair & Regenerate Edit

Your skin is a living, breathing organ constantly exposed to environmental stress, ageing factors, and daily wear and tear. To maintain its strength, resilience, and vitality, it needs a results-driven approach to repair and regeneration. At 1611 LABS, we believe in targeted, high-performance skincare that works with your skin’s biology to restore balance and promote…

Understanding Melanogenesis and Hyperpigmentation

Ever wondered how hyperpigmentation, dark spots, or discoloration develop after skin trauma or injury? Let’s dive into the fascinating science of melanogenesis, the process behind your skin’s pigment production. Step 1: Melanin Production Begins In the deeper layers of the skin, melanocytes (special pigment-producing cells) get to work when stimulated by factors like UV exposure,…

CELLULAR SENESCENCE AND AGEING

“Senescent cells, also called ‘zombie cells’, are aged cells which can no longer divide/replicate. But instead of being naturally removed, they remain in the skin, impacting their immediate environment, inducing a vicious circle of inflammation and premature ageing” Cellular senescence is a self-defence mechanism activated by our body in response to stress. ‘Senescence’ means the…

Everything you need to know about Retinoids

Retinoids, are derivatives of vitamin A that can be found in nature from animal and plant sources, although most commercially available retinoid products are produced synthetically in the lab. Retinoids are molecules that bind to and activate retinoic acid receptors to influence the proliferation (cell growth & division) and differentiation (unspecialized to specialized) of cells.…

Acetyl Glucosamine – The multi purpose active ingredient

N-acetyl-d-glucosamine (NAG) is an amino-monosaccharide that acts as a substrate precursor (one of it’s many functions) for the biosynthesis of polymers such as glycosaminoglycans  (i.e hyaluronic acid). It is easily incorporated in the skin layers due to its smaller molecule size. A hydrophilic molecule, mostly water soluble, this enhances it’s ability to be effectively delivered…

Bakuchiol: The sensitive skin alternative to retinol

  Bakuchiol, a meroterpene, is a phenolic compound with a monoterpene side chain. It belongs to a rare group of terpenoids in which the aromatic ring system is derived from a phenylpropane unit. It has no structural resemblance to retinoids, but has similar functionalities. Bakuchiol helps control inflammation by inhibiting/down regulating pro-inflammatory genes and enzymes,…

The Ultimate Protection: Vitamin C AOX Network

Formulated with stable, vegan 3-O- Ethyl Ascorbic Acid (EAA), to provide superior anti-oxidative action and effective cellular melanogenesis inhibition. EAA penetrates skin where it is metabolised into Ascorbic Acid. Due to this process, it’s efficacy is more pronounced than that of Ascorbic Acid. It’s slower release also means it’s less irritating and provides a slower but more…

Prebiotic Super Moisturiser

An ESSENTIAL first step in all routines.   Designed to help PROTECT. HYDRATE. BALANCE Incredibly lightweight, fast-absorbing prebiotic super moisturiser to help protect skin’s microbiome and rebalance the diversity of skin’s microbiota for a better skin barrier function. INULIN Formulated with Inulin, a clinically proven natural prebiotic that feeds selective organisms of the microbiota in…