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How to Adapt Your Routine in Your 40s, 50s & Beyond

Your skin is changing, but that doesn’t mean it’s failing.
In your 40s and 50s, hormonal shifts, collagen loss, and increased sensitivity call for more than guesswork. At 1611 LABS, we believe in skincare that adapts to your biology, your environment, and your stage of life.
With the right knowledge and skincare support, you can age well, keep your skin functioning optimally, and maintain radiance and resilience for decades to come.
What Actually Happens To Your Skin After 40?

In Your 40s: The Turning Point

By your 40s, most of the visible signs of ageing begin to take root; wrinkles, dryness, pigmentation, dullness, and skin starts to recover more slowly from inflammation and damage.
What’s Happening?
Collagen production drops by about 1% each year starting in your mid-30s, making skin thinner and less firm.
Estrogen declines in women during perimenopause, leading to a drop in skin hydration, elasticity, and plumpness.
Cell turnover slows, resulting in a duller complexion and uneven tone.
Melanin production becomes erratic, triggering age spots and uneven pigmentation.
What to do
Use retinoids to stimulate collagen and cell turnover.
Introduce peptides to support firmness and elasticity.
Focus on hydration strategies. Humectants like glycerin, urea and hyaluronic acid; and emollients like squalane or ceramides.
Always include broad-spectrum SPF. Sun damage accelerates visible ageing more than anything else.
In Your 50s: Hormonal Shifts & Structural Loss
This decade often marks menopause, leading to rapid hormonal changes that affect your skin in significant ways.
What’s Happening?
Collagen loss accelerates. Up to 30% of your collagen can be lost in the first 5 years post-menopause.
Skin becomes thinner and more fragile.
Sebum production slows, leading to drier skin that may feel rough or papery.
Barrier function weakens, which can trigger increased sensitivity or inflammation.
Volume loss in the face becomes more visible, affecting contours and firmness.
What to do
Use barrier-repair formulas with ceramides, and fatty acids.
Switch to gentle exfoliants (like lactic acid or PHAs) that can help brighten without disrupting the barrier.
Add firming peptides, or growth factors, to help support regeneration.
Always use formulas with a multi-step moisture layering (humectants + emollients + occlusives) to trap hydration.
Supplement your skincare with oral vitamins such as omega-3s, and vitamin D.
In Your 60s and Beyond: Cellular Energy & Maintenance
At this stage, your skin’s renewal systems are slower but still responsive to the right inputs.
What’s Happening?
Mitochondrial activity declines, reducing the skin’s ability to self-repair.
Elastin fibres degrade, contributing to sagging and deeper lines.
Microcirculation weakens, causing dullness and reduced oxygen/nutrient delivery to the skin.
Skin may become more reactive to environmental stressors or new products.
What to do
Boost skin energy with antioxidants like CoQ10, ferulic acid, and polyphenols.
Maintain a minimal but high-performance routine focused on barrier strength, hydration, and regeneration.
Avoid aggressive treatments that can damage fragile skin, and instead opt for biotech and biomimetic actives, and barrier-focused care.
Incorporate regular massage or facial tools to support circulation and muscle tone.
Hydrate from within – drink water, reduce sugar, and increase antioxidant-rich foods.
How to Pause Visible Signs of Ageing
You can’t stop the clock, but you can slow the effects it has on your skin. At 1611 LABS, we recommend a science-driven, formula-focused approach.
Understand Your Skin’s Unique Ageing Pattern
Our expert consultations help analyse age, environment, diet, and hormone shifts to personalise your treatment plan. Ageing looks different for everyone, your skincare should reflect that.
Treat the Skin, Not the Decade
Don’t just buy products “for 50+.”
Target function: repair, plump, brighten, strengthen.
Use multi-functional products that evolve with your needs.
Consistency Beats Trends
A minimal, consistent routine will outperform trendy ingredients. Your skin thrives on stability and daily support.
Use Ingredients That Do the Work
We focus on actives with deep clinical validation –
Retinal for collagen and texture
Niacinamide for tone, repair, and sensitivity
Biotech derived actives + Peptides for regeneration
Ceramides + omega-rich oils for barrier strength
SPF 50+ daily – NON-NEGOTIABLE